abstract：:Monocytes from patients with definite or classical rheumatoid arthritis show a significantly higher release of O2-radicals in the chemiluminescence assay (2925 X 10(3) cpm) than those of healthy volunteers (267 X 10(3) cpm) (p = 0.01). This difference does not appear in a similar test with granulocytes, which in both ...

journal_title：Zeitschrift fur Rheumatologie

authors： Meske S,Maly FE,Estefan M,Müller W

更新日期：1985-01-01 00:00:00

abstract：:Among all laboratory parameters used today in the assessment of activity and progression of rheumatoid arthritis erythrocyte sedimentation rate (ESR) can only be recommended reservedly. ESR is influenced by anemia, reduction of plasma fibrinogen, dysproteinemia and by the concentration of acute phase proteins. Quantif...

journal_title：Zeitschrift fur Rheumatologie

authors： Chlud K

更新日期：1985-01-01 00:00:00

abstract：:Performing histo-morphologic studies of knee joints in several hundred mice of the strains C57 black, STR/1N and MAGf, showing a disposition for spontaneous osteo-arthrosis, we found tentative reparative processes in many cases. There was a proliferation of cartilage and of the synovial membrane, mostly in the periphe...

journal_title：Zeitschrift fur Rheumatologie

authors： Wilhelmi G,Schneider-Faust R

更新日期：1984-09-01 00:00:00

abstract：:Peripheral blood lymphocytes of patients with rheumatoid arthritis, psoriatic arthritis and healthy controls, isolated by a ficoll density gradient, were incubated with different concentrations of histamine, cimetidine and diphenhydramine (DPH) and simultaneously stimulated with phytohemagglutinine (PHA). In compariso...

journal_title：Zeitschrift fur Rheumatologie

authors： Manger BJ,Stix R,Platzer E,Hess B,Kalden JR

更新日期：1984-07-01 00:00:00

abstract：:Seronegative rheumatoid arthritis (RA) patients have increased proportions of OKT-4+ (helper) T cells and diminished proportions of OKT-8+ (suppressor/cytotoxic) T cells in the peripheral blood. This phenomenon corresponds to diminished inhibition of B cell activation by peripheral blood lymphocytes (PBL). Seropositiv...

journal_title：Zeitschrift fur Rheumatologie

authors： Lemm G,Warnatz H

更新日期：1984-05-01 00:00:00

abstract：:Due to the relative increase of age-diabetes and to the different forms of rheumatic diseases, long-term medicament therapy and the question of possible interactions between oral antidiabetic drugs ( OAD ) and nonsteroidal anti-inflammatory drugs (NSAID) become more important. Unfortunately there exist studies on most...

journal_title：Zeitschrift fur Rheumatologie

authors： Knüsel O

更新日期：1984-03-01 00:00:00

abstract：:Eight human femoral heads, surgically removed from patients with the clinical diagnosis: coxarthrosis or necrosis, were examined. In six of these we found severe arthrosis combined with synovitis and pannus formation. The pannus appeared as granulation tissue or fibrous connective tissue covering the surface of the ca...

journal_title：Zeitschrift fur Rheumatologie

authors： Pataki A,Lothe K,Spycher MA,Rüttner JR,Cserhati MD

更新日期：1983-11-01 00:00:00

abstract：:In a double-blind study, glycosaminoglycan polysulfate (GAGPS, Arteparon) was compared to saline solution: both preparations were applied intramuscularly in two groups of 70 patients, each over a period of 8 weeks. The patients were suffering from pain and impaired function of the knee and hip joints. To assess the th...

journal_title：Zeitschrift fur Rheumatologie

authors： Siegmeth W,Radi I

更新日期：1983-07-01 00:00:00

abstract：:Light microscopic examination of histological sections of synovial membrane from patients with rheumatoid arthritis revealed that prolonged administration of corticosteroids had an inhibiting effect on the participation of lymphocytes and histiocytes in inflammatory infiltrates, as well as on the hypertrophy of synovi...

journal_title：Zeitschrift fur Rheumatologie

authors： Soren A,Cooper NS,Rosenberger JL,Waugh TR

更新日期：1983-05-01 00:00:00

abstract：:The data from a combined pathological and kinesiological investigation in autopsy specimens of the cervical spine were used to test whether adjacent motion segments compensate for loss of mobility at a given level. In the segments adjacent to a low-mobile one no evidence was found of compensatory hypermobility, of an ...

journal_title：Zeitschrift fur Rheumatologie

authors： Eulderink F,ten Have HA

更新日期：1982-11-01 00:00:00

abstract：:Binding of gold to serum proteins of patients treated with Na-aurothiomalate (AM), gold keratinate (GK) and triethylphosphine gold (PG) was compared. In addition the pattern of distribution of gold in serum of healthy donors after in vitro incubation with these compounds and with tetrachlorogoldacid (GC) was studied. ...

journal_title：Zeitschrift fur Rheumatologie

authors： Herrlinger JD,Weikert W

更新日期：1982-09-01 00:00:00

abstract：:The development of synovitis was studied in 64 rabbits with experimentally produced allergic arthritis and in 30 rabbits with experimentally produced non-allergic arthritis. The results are compared with the morphological changes of the synovial membrane in rheumatoid arthritis, especially in early stages, known from ...

journal_title：Zeitschrift fur Rheumatologie

authors： Püschel W

更新日期：1982-01-01 00:00:00

abstract：:Polyarthralgias are widely common complaints. In earlier stages it might be difficult to state the right diagnosis. Differential diagnosis is absolutely necessary for starting in time with the right treatment. Out of a great clinical material the following diseases causing mono-, oligo- or polyarthralgia were discusse...

journal_title：Zeitschrift fur Rheumatologie

authors： Singer F

更新日期：1982-01-01 00:00:00

abstract：:OM 8930, a bacterial product with immunostimulatory capacities, was studied for its efficacy in the long-term treatment of rheumatoid arthritis (RA). Ten (10) patients with active seropositive rheumatoid arthritis were treated intermittently for six months with the agent and were evaluated according to clinical, labor...

journal_title：Zeitschrift fur Rheumatologie

authors： Rosenthal M,Plattner S

更新日期：1981-09-01 00:00:00

abstract：:Eighteen patients suffering from chronic rheumatoid arthritis were selected for the present study. Plasma levels of stress hormones like catecholamines and cortisol were found to be elevated. At the same time reduction in percentage of E-rosette forming lymphocytes and an elevation in levels of major serum immunoglobu...

journal_title：Zeitschrift fur Rheumatologie

authors： Kumar R,Singh LM,Vaidya MP

更新日期：1981-05-01 00:00:00

abstract：:By means of the 99m-Tc-pertechnitate joint scintigraphy the authors try to document the effect of antirheumatic drugs in 62 patients with rheumatoid arthritis. By measuring the changes of the synovial blood circulation, conclusions are drawn as to the degree of inflammation. When trying to make a quantitative assessme...

journal_title：Zeitschrift fur Rheumatologie

authors： Kafarnik D,Semmler U,Pfannenstiel P,Miehlke K

更新日期：1981-03-01 00:00:00

abstract：:The antidesoxyribonuclease B reaction shows in persons of all classes of age examined a similar distribution of titres as the antistreptolysin reaction. The anti DNase B titres however are mostly lower than the titres of the antistreptolysin reaction, except in the group of children, 6 to 17 years of age, suffering fr...

journal_title：Zeitschrift fur Rheumatologie

authors： Otto R,Richter M,Scholz E,Neumann G

更新日期：1981-01-01 00:00:00

abstract：:The biochemical defect leading to alcaptonuria is well known. However, the pathogenesis of ochronotic arthropathy is poorly understood. The present ultrastructural study elucidated the localization of ochronotic pigment in the articular cartilage and evidence was found that suggests a pathway for cartilage destruction...

journal_title：Zeitschrift fur Rheumatologie

authors： Mohr W,Wessinghage D,Lenschow E

更新日期：1980-03-01 00:00:00

abstract：:This paper concerns a radiological and postmortem study of an 81-year-old woman with diffuse intervertebral osteochondrosis (T12-L1 severe erosion) in association with generalized osteoarthritis and articular chondrocalcinosis. Varying degrees of cartilage plate flaws with cartilaginous Schmorl's nodes and vertebral p...

journal_title：Zeitschrift fur Rheumatologie

authors： Lagier R,Mac Gee W

更新日期：1979-11-01 00:00:00

abstract：:The case described concerns a patient initially presenting the clinical symptoms of rheumatoid arthritis, including the presence of nodules, and slowly developing into systemic lupus erythematosus (SLE). Besides the signs of chronic inflammation in the synovial tissue, many granulocytes and PAS-positive macrophages we...

journal_title：Zeitschrift fur Rheumatologie

authors： Meijers KA,Eulderink F,van de Putte LB,Wiersema-van Gogh H,de Vries E,Cats A

更新日期：1979-07-01 00:00:00

abstract：:ECG from 200 patients with radiologically and clinically definite rheumatoid arthritis were compared with those from a healthy group with the same age and sex distribution. The frequency of pathological changes of the ECG was found to be the same in both groups. Therefore doubt remains whether the pathological changes...

journal_title：Zeitschrift fur Rheumatologie

authors： Droste U,Zimmermann H

更新日期：1979-07-01 00:00:00

abstract：:Serum protein binding of naproxen is considerably reduced in patients with renal insufficiency. The hypothetical plasma concentration at time zero and the half life are not significantly altered in uremic patients in comparison with healthy subjects when the drug is given orally. This suggests an increased pharmacodyn...

journal_title：Zeitschrift fur Rheumatologie

authors： Held H

更新日期：1979-03-01 00:00:00

abstract：:The photometric latex test (PLT) for the detection of rheumatoid factors (RF) has been correlated with the sensitized sheep cell test (SSC) and the latex slide test (LST). A total of 377 sera from patients with rheumatoid arthritis (RA) and 120 sera from control subjects were examined. When the PLT was carried out on ...

journal_title：Zeitschrift fur Rheumatologie

authors： Dezelić N,Zergollern V,Dezelić G,Dürrigl T,Jurak H,Vitaus M,Androić S

更新日期：1978-03-01 00:00:00

abstract：:D-penicillamine treatment of 50 patients with rheumatoid arthritis with negative ANF tests, was followed by means of protein disk electrophoresis of the urine. In the beginning the urine proteins were analysed every 4 weeks, later at intervals of 3 to 6 months. A glomerular proteinuria, caused by an immune-complex nep...

journal_title：Zeitschrift fur Rheumatologie

authors： Rautenstrauch H

更新日期：1977-11-01 00:00:00

abstract：:1436 young men were investigated clinically and radiologically for rheumatic sacro iliitis. In two men (1.4%) definite bilateral sacro iliitis was diagnosed. In 18 cases (12.5%) the signs were not sufficient to make a definite diagnosis. They were regarded as suspected iliitis. For comparison the cards of 6138 patient...

journal_title：Zeitschrift fur Rheumatologie

authors： Yenal O,Usman ON,Yassa K,Uyar A,Agbaba S

更新日期：1977-09-01 00:00:00

abstract：:Five to 9 months after a comparative study of 2 groups of patients with coxarthrosis and gonarthrosis, 69 individuals (group 1) receiving Arteparon forte injections and physical therapy and 46 persons (group 2) with physical therapy only, questioneer with specific questions was sent out. From 72 questioneers mailed 55...

journal_title：Zeitschrift fur Rheumatologie

authors： Rau E,Schmid C,Bach GL

更新日期：1977-07-01 00:00:00

abstract：:30 patients with hepatitis, 50 patients with gynecological diseases, and 100 with urological diseases were investigated with regards to lumbago to find out whether there is a correlation between the internal disease and the signs of low back pain. The patients were compared with a control group of 33 healthy people. T...

journal_title：Zeitschrift fur Rheumatologie

authors： Tilscher H,Bogner G,Landsiedl F

更新日期：1977-05-01 00:00:00

abstract：:The effect of D-penicillamine, given for 14 days in doses of 100 mg/kg and 225 mg/kg, upon the collagen metabolism of skin and bone tissues was studied in rats. The smaller dosage of D-penicillamine did not effect the collagen synthesis in skin or bone. When the higher dosage was used, however, an increase of collagen...

journal_title：Zeitschrift fur Rheumatologie

authors： Trnavská Z,Trnavský K

更新日期：1977-05-01 00:00:00

abstract：:The sulfhydryl groups are chemically active parts of the protein molecule and participate in many important biochemical and metabolic processes. The present material comprised 132 patients with rheumatoid arthritis, 104 patients with other diseases and 44 controls. The patients with rheumatoid arthritis had decreased ...

journal_title：Zeitschrift fur Rheumatologie

authors： Haataja M,Kalliomäki JL

更新日期：1977-03-01 00:00:00

abstract：UNLABELLED:Influence of anti-rheumatic drugs on human lymphocytes, especially T and B cell membranes, was studies with D-penicillamine, aurothiomalate, dexamethasone, cyclophosphamide, mitomycin C and aspirin. METHOD:Peripheral blood obtained from five healthy individuals and lymphocytes were separated by centrifugati...

journal_title：Zeitschrift fur Rheumatologie

authors： Yoshino S,Ishiyama I

更新日期：1977-01-01 00:00:00

abstract：:Fiftythree patients with progressive systemic sclerosis were studied. Four of them (3 males) had the diffuse form of the disease. The skin manifestation of this clinical picture is characterized by diffuse progression of the cutaneous sclerosis over almost the whole body surface, except for the hands where it eventual...

journal_title：Zeitschrift fur Rheumatologie

authors： Giordano M,Ara M,Capelli L,Tirri G,Vatti M

更新日期：1976-07-01 00:00:00

abstract：:The correlation of the determination of antinuclear antibodies, as shown by consumption tests and immunofluorescence was investigated in a collective of 100 sera of patients suspected for SLE, collagenosis and rheumatoid arthritis, sent for routine screening investigation. The results of both methods correlated in 78%...

journal_title：Zeitschrift fur Rheumatologie

authors： Weheba AS

更新日期：1976-05-01 00:00:00

abstract：:Several immuno-pathological aspects of polyarthritis following experimental infection with erysipelas in pigs were studied for two years. Aseptic and specifically pathogenfree animals were infected subcutaneously and intravenously-intraarticularly with living erysipeals bacteria (erysipelothrix rhusiopathiae) of serot...

journal_title：Zeitschrift fur Rheumatologie

authors： Trautwein G,Seidler D,Schulz LC,Drommer W,Weiss R,Böhm KH

更新日期：1976-05-01 00:00:00

abstract：:Eight patients with SLE were found on clinical and roentgenological grounds or by respiratory function tests to have evidence of lung involvement. Great discrepancies were noted between clinical findings and the results of the respiratory function tests on the one hand and lacking or discrete radiological changes on t...

journal_title：Zeitschrift fur Rheumatologie

authors： Görlitz N,Berzon R,Rössner B,Wessel G,Jäckel R

更新日期：1976-03-01 00:00:00

abstract：:278 patients with ankylosing spondylitis have been studied in order to find a basis for prognosis by setting a mobility function index of the vertebral column. This index does not depend on manifestation age or on the blood sedimentation rate. It increases with progression of x-ray findings. A coincidence of impaired ...

journal_title：Zeitschrift fur Rheumatologie

authors： Schöffel J,Pohl W

更新日期：1975-11-01 00:00:00

abstract：:Biochemical studies of rats with mycoplasma arthritis revealed new findings in pathogenesis and pathophysiology. Preliminary examinations showed that mycoplasmas release specific endonucleases and exonucleases. In evaluating the isoenzymes of the lactate dehydrogenases, malate dehydrogenases as well as of the esterase...

journal_title：Zeitschrift fur Rheumatologie

authors： Klein G

更新日期：1975-05-01 00:00:00

abstract：:In an intraindividual series of investigation consisting of 30 patients with rheumatoid arthritis the effect of gold therapy (Aurothioglucose) has been proved controlling biochemical and clinical parameters. Controls of the function-index by Steinbrocker et al. have shown a significant improvement in comparison with t...

journal_title：Zeitschrift fur Rheumatologie

authors： Knoche U,Wagner H,Hauss WH

更新日期：1975-05-01 00:00:00